Solanum aculeastrum is commonly planted as a hedge.
The spines are hard enough to rupture tyres and stems are placed across the roads to prevent vehicle access.
Some varieties have edible fruit.
Medicinal uses include the treatment of swelling joints in fingers with fruit and leaves to prevent gangrene setting in, drying and pounding roots and taking a little on tongue twice daily for an enlarged spleen, and use as eyewash.
Vernacular names include the commonly quoted Mutugunda, Omutugunda, and Mutura, as well as more rare Umotobo, Kood (Lateba), Niva fera-fera, Temberere, Imitobotobo (Kirundi), and Motobatoba (Ruanda).