Darwin Tree of Life project
The Darwin Tree of Life project has an ambitious target of sequencing the DNA barcodes and full genomes of all 66,000+ described UK species and is the UK’s contribution to the Earth Biogenome Project.
The project is led by the Wellcome Sanger Institute and is a collaboration between world-leading scientific institutions, including the Natural History Museum.
More than ever, it is critical that we preserve biodiversity. Genomics can be used to understand and describe species, and this knowledge can contribute to conservation efforts that are mitigating the impacts of negative environmental change.
The Earth has experienced five mass extinction events and we are currently in the sixth. Unlike previous great extinctions, humans are driving this event. Humans are changing the climate, destroying habitats, changing land and sea use, polluting and introducing invasive species.
We can work towards securing and protecting biodiversity for future generations through the development of new technologies and multidisciplinary collaborations.
The Darwin Tree of Life pilot
The Darwin Tree of Life project is in a pilot phase from February 2020 to August 2022. In this period we will:
- generate chromosomally complete assemblies for all ~4,000 families of eukaryotic taxa native to the UK
- DNA barcode 10,000 species from these families at the Natural History Museum, London, contributing to accurate and comprehensive genomic databases
- publish all data on an open access FAIR data, available worldwide.
Wellcome Trust, total value £9,362,420 (£868,763 to Museum)
February 2020 - August 2022
- Natural History Museum
- The Marine Biological Association, United Kingdom
- Royal Botanic Gardens Kew
- Royal Botanic Gardens Edinburgh
- The Earlham Institute
- The European Bioinformatics Institute
- The University of Oxford and its Wytham Woods field station
- The University of Edinburgh and Edinburgh Genomics
- The University of Cambridge
How do we collect and sequence 66,000 species?
The UK is one of the most comprehensively studied regions globally, owing to a network of professionals and skilled enthusiasts. There are over 66,000 described species of British fauna and flora. This project will further increase our knowledge of British biodiversity.
Before sampling begins, it is critical to have a comprehensive checklist of UK species. The Natural History Museum has, for over a decade, maintained the UK's most comprehensive database of taxonomy and nomenclature, which provides the foundation for most biological recording systems.
There are four key steps to the molecular description of all eukaryotic species in the UK:
- Specimen collection: Sampling excursions target hotspots of biodiversity across the country, maximising specimen diversity.
- Identification: Taxonomic species names are assigned to specimens by experts across the partner institutions.
- DNA barcoding: Specimens will be sent to the Natural History Museum for barcoding, voucher specimens will be incorporated into the collections.
- Full genomic sequencing: Specimens will be sent to the Wellcome Sanger Institute to assemble and annotate full genomes.
Looking to get involved?
Are you are interested in engaging with this project, or represent an external group interested in working with the Museum's Darwin Tree of Life team?
Do you have a sampling enquiry?
The Darwin Tree of Life project involves collecting specimens across a wide range of taxa.
Here, a light trap collects insects by the River Wye.