The reactivity and toxicity of engineered nanoparticles: risks to the environment and human health
Project aim
To identify the potential risks posed by engineered nanomaterial to the environment and human health by comprehensively addressing 5 key questions:
- How does the environment into which nanoparticles are released affect their physicochemical properties and their bioreactivity?
- How does this impact on their bioavailability – their ability to interact with and/or penetrate mammalian and aquatic cells and organisms, and will bioavailability result in toxicity?
- Is there a pattern of cellular reactivity and/or toxicity related to physicochemical properties - in other words, a hierarchy of activity?
- What combination of conditions discovered in 1-3 above are most likely to pose a risk to human health and the environment?
- How can this information be incorporated in a risk assessment model?
An international team
We have assembled a team of experts from across the EU and the US whose combined expertise can address these questions in depth.
The project has a dedicated website at NanoReTox.