Prof Ian Barnes

Prof Ian Barnes

Research Leader

Department: Earth Sciences
Division: ES Vertebrates and Anthropology Palaeobiology
Contact: email
Phone: +44 207 942 6892

Specialisms

Ancient DNA, Biomolecular Archaeology., Evolutionary Biology, Late Pleistocene, Population Genetics, Taxonomy

Summary

I am a molecular evolutionary biologist who works with museum collections, archaeological and paleontological material. I use modern and ancient DNA, together with protein and isotope data, to understand how organisms adapt and react to changes in their environment.

Qualifications

Degrees

D.Phil., University of York, UK, 1994 - 1998

B.Sc., University of Bradford, UK, 1990 - 1994

Employment history

Academic

Senior Lecturer, Reader and Professor, Royal Holloway University of London, Biological Sciences, UK, 2005 - 2013

Wellcome Trust Bioarchaeology Fellow, University College London, Biology, UK, 2002 - 2005

Postdoctoral Research Assistant, University of Oxford, Biological Anthropology, UK, 1999 - 2002

Research Associate, University College London, Bacteriology, UK, 1998 - 1999

Publications

Welker F, Collins MJ, Thomas JA, Wadsley M, Brace S, Cappellini E, Turvey ST, Reguero M, Gelfo JN, Kramarz A, Burger J, Thomas-Oates J, Ashford DA, Ashton PD, Rowsell K, Porter DM, Kessler B, Fischer R, Baessmann C, Kaspar S, Olsen JV, Kiley P, Elliott JA, Kelstrup CD, Mullin V, Hofreiter M, Willerslev E, Hublin J-J, Orlando L, Barnes I, MacPhee RDE (2015) Ancient proteins resolve the evolutionary history of Darwin’s South American ungulates. Nature, doi: 10.1038/nature14249

Brace S, Barnes I, Kitchener AC, Serjeantson D, Turvey ST (2014) Late Holocene range collapse in a former British seabird species. Journal of Biogeography, 41 (8): 1583 - 1589. doi: 10.1111/jbi.12305

Barnett R, Yamaguchi N, Shapiro B, Ho SYW, Barnes I, Sabin R, Werdelin L, Cuisin J, Larson G (2014) Revealing the maternal demographic history of Panthera leo using ancient DNA and a spatially explicit genealogical analysis. BMC evolutionary biology, 14 (1): 70 - 70. doi: 10.1186/1471-2148-14-70

Rasmussen M, Anzick SL, Waters MR, Skoglund P, DeGiorgio M, Stafford Jr TW, Rasmussen S, Moltke I, Albrechtsen A, Doyle SM, others (2014) The genome of a Late Pleistocene human from a Clovis burial site in western Montana. Nature, 506 (7487): 225 - 229. doi: 10.1038/nature13025

Meiri M, Lister AM, Collins MJ, Tuross N, Goebel T, Blockley S, Zazula GD, van Doorn N, Guthrie RD, Boeskorov GG, others (2014) Faunal record identifies Bering isthmus conditions as constraint to end-Pleistocene migration to the New World. Proceedings of the Royal Society B: Biological Sciences, 281 (1776): 20132167 - 20132167. doi: 10.1098/rspb.2013.2167

Heintzman PD, Elias SA, Moore K, Paszkiewicz K, Barnes I (2014) Characterizing DNA preservation in degraded specimens of Amara alpina (Carabidae: Coleoptera). Molecular ecology resources, 14 (3): 606 - 615. doi: 10.1111/1755-0998.12205

von Holstein ICC, Ashby SP, van Doorn NL, Sachs SM, Buckley M, Meiri M, Barnes I, Brundle A, Collins MJ (2014) Searching for Scandinavians in pre-Viking Scotland: molecular fingerprinting of Early Medieval combs. Journal of Archaeological Science, 41 : 1 - 6. doi: 10.1016/j.jas.2013.07.026

Palkopoulou E, Dalén L, Lister AM, Vartanyan S, Sablin M, Sher A, Edmark VN, Brandström MD, Germonpré M, Barnes I, others (2013) Holarctic genetic structure and range dynamics in the woolly mammoth. Proceedings of the Royal Society B: Biological Sciences, 280 (1770): 20131910 - 20131910. doi: 10.1098/rspb.2013.1910

Meiri M, Lister AM, Higham TFG, Stewart JR, Straus LG, Obermaier H, Gonzalez Morales MR, Marín-Arroyo AB, Barnes I (2013) Late-glacial recolonization and phylogeography of European red deer (Cervus elaphus L.). Molecular ecology, 22 (18): 4711 - 4722. doi: 10.1111/mec.12420

Brace S, Palkopoulou E, Dalén L, Lister AM, Miller R, Otte M, Germonpré M, Blockley SPE, Stewart JR, Barnes I (2012) Serial population extinctions in a small mammal indicate Late Pleistocene ecosystem instability. Proceedings of the National Academy of Sciences, 109 (50): 20532 - 20536. doi: 10.1073/pnas.1213322109

Nyström V, Humphrey J, Skoglund P, McKEOWN NIALLJ, Vartanyan S, Shaw PW, Lidén K, Jakobsson M, Barnes I, Angerbjörn A, others (2012) Microsatellite genotyping reveals end-Pleistocene decline in mammoth autosomal genetic variation. Molecular ecology, 21 (14): 3391 - 3402. doi: 10.1111/j.1365-294X.2012.05525.x

Brace S, Barnes I, Powell A, Pearson R, Woolaver LG, Thomas MG, Turvey ST (2012) Population history of the Hispaniolan hutia Plagiodontia aedium (Rodentia: Capromyidae): testing the model of ancient differentiation on a geotectonically complex Caribbean island. Molecular ecology, 21 (9): 2239 - 2253. doi: 10.1111/j.1365-294X.2012.05514.x

Barnes I, Duda A, Pybus OG, Thomas MG (2011) Ancient urbanization predicts genetic resistance to tuberculosis. Evolution, 65 (3): 842 - 848. doi: 10.1111/j.1558-5646.2010.01132.x

Edwards CJ, Suchard MA, Lemey P, Welch JJ, Barnes I, Fulton TL, Barnett R, O Connell TC, Coxon P, Monaghan N, others (2011) Ancient hybridization and an Irish origin for the modern polar bear matriline. Current Biology, 21 (15): 1251 - 1258. doi: 10.1016/j.cub.2011.05.058

Ho SYW, Lanfear R, Phillips MJ, Barnes I, Thomas JA, Kolokotronis S-O, Shapiro B (2011) Bayesian estimation of substitution rates from ancient DNA sequences with low information content. Systematic biology, 60 (3): 366 - 375. doi: 10.1093/sysbio/syq099

Teacher AGF, Thomas JA, Barnes I (2011) Modern and ancient red fox (Vulpes vulpes) in Europe show an unusual lack of geographical and temporal structuring, and differing responses within the carnivores to historical climatic change. BMC evolutionary biology, 11 (1): 214 - 214. doi: 10.1186/1471-2148-11-214

Workman C, Dalen L, Vartanyan S, Shapiro B, Kosintsev P, Sher A, Gotherstrom A, Barnes I (2011) Population-level genotyping of coat colour polymorphism in woolly mammoth (< i> Mammuthus primigenius). Quaternary Science Reviews, 30 : 2304 - 2308. doi: 10.1016/j.quascirev.2010.08.020

Stewart JR, Lister AM, Barnes I, Dalén L (2010) Refugia revisited: individualistic responses of species in space and time. Proceedings of the Royal Society B: Biological Sciences, 277 (1682): 661 - 671. doi: 10.1098/rspb.2009.1272

Hofreiter M, Barnes I (2010) Diversity lost: are all Holarctic large mammal species just relict populations?. BMC biology, 8 (1): 46 - 46. doi: 10.1186/1741-7007-8-46

Tuross N, Kirsanow K, Barnes I (2009) Limits and possibilities for subsistence and climate reconstruction based on organic and inorganic oxygen isotopes in vertebrate calcified tissues. GEOCHIMICA ET COSMOCHIMICA ACTA, 73 (13)

Hong HA, Khaneja R, Tam NMK, Cazzato A, Tan S, Urdaci M, Brisson A, Gasbarrini A, Barnes I, Cutting SM (2009) Bacillus subtilis isolated from the human gastrointestinal tract. Research in Microbiology, 160 (2): 134 - 143. doi: 10.1016/j.resmic.2008.11.002

Barnett R, Shapiro B, Barnes IAN, Ho SYW, Burger J, Yamaguchi N, Higham TFG, WHEELER H, Rosendahl W, Sher AV, others (2009) Phylogeography of lions (Panthera leo ssp.) reveals three distinct taxa and a late Pleistocene reduction in genetic diversity. Molecular Ecology, 18 (8): 1668 - 1677. doi: 10.1111/j.1365-294X.2009.04134.x

Chatterjee HJ, Ho SYW, Barnes I, Groves C (2009) Estimating the phylogeny and divergence times of primates using a supermatrix approach. BMC Evolutionary Biology, 9 (1): 259 - 259. doi: 10.1186/1471-2148-9-259

Haile J, Froese DG, MacPhee RDE, Roberts RG, Arnold LJ, Reyes AV, Rasmussen M, Nielsen R, Brook BW, Robinson S, others (2009) Ancient DNA reveals late survival of mammoth and horse in interior Alaska. Proceedings of the National Academy of Sciences, 106 (52): 22352 - 22357. doi: 10.1073/pnas.0912510106

Hong HA, Khaneja R, Tam NMK, Cazzato A, Tan S, Urdaci M, Brisson A, Gasbarrini A, Barnes I, Cutting SM (2009) < i> Bacillus subtilis isolated from the human gastrointestinal tract. Research in microbiology, 160 : 134 - 143.

Valdiosera CE, García-Garitagoitia JL, Garcia N, Doadrio I, Thomas MG, Hänni C, Arsuaga J-L, Barnes I, Hofreiter M, Orlando L, others (2008) Surprising migration and population size dynamics in ancient Iberian brown bears (Ursus arctos). Proceedings of the National Academy of Sciences, 105 (13): 5123 - 5128. doi: 10.1073/pnas.0712223105

Barnes I, Shapiro B, Lister A, Kuznetsova T, Sher A, Guthrie D, Thomas MG (2007) Genetic Structure and Extinction of the Woolly Mammoth,< i> Mammuthus primigenius. Current Biology, 17 (12): 1072 - 1075. doi: 10.1016/j.cub.2007.05.035

Bekele E, Geleta M, Dagne K, Jones AL, Barnes I, Bradman N, Thomas MG (2007) Molecular phylogeny of genus Guizotia (Asteraceae) using DNA sequences derived from ITS. Genetic Resources and Crop Evolution, 54 (7): 1419 - 1427. doi: 10.1007/s10722-006-9126-0

Thomas MG, Barnes I, Weale ME, Jones AL, Forster P, Bradman N, Pramstaller PP (2007) New genetic evidence supports isolation and drift in the Ladin communities of the South Tyrolean Alps but not an ancient origin in the Middle East. European Journal of Human Genetics, 16 (1): 124 - 134. doi: 10.1038/sj.ejhg.5201906

Valdiosera CE, García N, Anderung C, Dalén L, CRÉGUT-BONNOURE E, KAHLKE R-D, Stiller M, Brandström M, Thomas MG, Arsuaga JL, others (2007) Staying out in the cold: glacial refugia and mitochondrial DNA phylogeography in ancient European brown bears. Molecular Ecology, 16 (24): 5140 - 5148. doi: 10.1111/j.1365-294X.2007.03590.x

Wilson AS, Taylor T, Ceruti MC, Chavez JA, Reinhard J, Grimes V, Meier-Augenstein W, Cartmell L, Stern B, Richards MP, others (2007) Stable isotope and DNA evidence for ritual sequences in Inca child sacrifice. Proceedings of the National Academy of Sciences, 104 (42): 16456 - 16461. doi: 10.1073/pnas.0704276104

Barnes I, Thomas MG (2006) Evaluating bacterial pathogen DNA preservation in museum osteological collections. Proceedings of the Royal Society B: Biological Sciences, 273 (1587): 645 - 653. doi: 10.1098/rspb.2005.3339

Barnett R, Yamaguchi N, Barnes I, Cooper A (2006) Lost populations and preserving genetic diversity in the lion Panthera leo: implications for its ex situ conservation. Conservation Genetics, 7 (4): 507 - 514. doi: 10.1007/s10592-005-9062-0

Barnett R, Yamaguchi N, Barnes I, Cooper A (2006) The origin, current diversity and future conservation of the modern lion (Panthera leo). Proceedings of the Royal Society B: Biological Sciences, 273 (1598): 2119 - 2125. doi: 10.1098/rspb.2006.3555

Chatterjee HJ, Barnes I, Upchurch P, Shore R (2006) Primate evolution in Southeast Asia.. AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY, : 74 - 75.

Barnett R, Barnes I, Phillips MJ, Martin LD, Harington CR, Leonard JA, Cooper A (2005) Evolution of the extinct Sabretooths and the American cheetah-like cat. Current Biology, 15 (15)doi: 10.1016/j.cub.2005.07.052

Bunce M, Szulkin M, Lerner HRL, Barnes I, Shapiro B, Cooper A, Holdaway RN (2005) Ancient DNA provides new insights into the evolutionary history of New Zealand’s extinct giant eagle. PLoS biology, 3 (1)doi: 10.1371/journal.pbio.0030009

Gilbert MTP, Bandelt H-J, Hofreiter M, Barnes I (2005) Assessing ancient DNA studies. Trends in Ecology & Evolution, 20 (10): 541 - 544. doi: 10.1016/j.tree.2005.07.005

Gilbert MTP, Barnes I, Collins MJ, Smith C, Eklund J, Goudsmit J, Poinar H, Cooper A (2005) Long-term survival of ancient DNA in Egypt: Response to Zink and Nerlich (2003). American journal of physical anthropology, 128 (1): 110 - 114. doi: 10.1002/ajpa.20045

Krause J, Dear PH, Pollack JL, Slatkin M, Spriggs H, Barnes I, Lister AM, Ebersberger I, Pääbo S, Hofreiter M (2005) Multiplex amplification of the mammoth mitochondrial genome and the evolution of Elephantidae. Nature, 439 (7077): 724 - 727. doi: 10.1038/nature04432

Lister AM, Edwards CJ, Nock DAW, Bunce M, Van Pijlen IA, Bradley DG, Thomas MG, Barnes I (2005) The phylogenetic position of the ‘giant deer’Megaloceros giganteus. Nature, 438 (7069): 850 - 853. doi: 10.1038/nature04134

Shapiro B, Drummond AJ, Rambaut A, Wilson MC, Matheus PE, Sher AV, Pybus OG, Gilbert MTP, Barnes I, Binladen J, others (2004) Rise and fall of the Beringian steppe bison. Science, 306 (5701): 1561 - 1565. doi: 10.1126/science.1101074

Willerslev E, Hansen AJ, Rønn R, Brand TB, Barnes I, Wiuf C, Gilichinsky D, Mitchell D, Cooper A (2004) Long-term persistence of bacterial DNA. Current Biology, 14 (1)doi: 10.1016/j.cub.2003.12.012

Gilbert MTP, Hansen AJ, Willerslev E, Rudbeck L, Barnes I, Lynnerup N, Cooper A (2003) Characterization of genetic miscoding lesions caused by postmortem damage. The American Journal of Human Genetics, 72 (1): 48 - 61. doi: 10.1086/345379

Gilbert MTP, Willerslev E, Hansen AJ, Barnes I, Rudbeck L, Lynnerup N, Cooper A (2003) Distribution patterns of postmortem damage in human mitochondrial DNA. The American Journal of Human Genetics, 72 (1): 32 - 47. doi: 10.1086/345378

Barnes I, Matheus P, Shapiro B, Jensen D, Cooper A (2002) Dynamics of Pleistocene population extinctions in Beringian brown bears. Science, 295 (5563): 2267 - 2270. doi: 10.1126/science.1067814

Willerslev E, Mourier T, Hansen AJ, Christensen B, Barnes I, Salzberg SL (2002) Contamination in the draft of the human genome masquerades as lateral gene transfer. Mitochondrial DNA, 13 (2): 75 - 76. doi: 10.1080/10425170290023392

Poinar HN, Kuch M, Sobolik KD, Barnes I, Stankiewicz AB, Kuder T, Spaulding WG, Bryant VM, Cooper A, Pääbo S (2001) A molecular analysis of dietary diversity for three archaic Native Americans. Proceedings of the National Academy of Sciences, 98 (8): 4317 - 4322. doi: 10.1073/pnas.061014798

Spigelman M, Barnes I, Holton J, Vaira D, Thomas MG (2001) Long-term DNA survival in ethanol-preserved archival material.. Annals of the Royal College of Surgeons of England, 83 (4): 283 - 283.

Barnes I, Holton J, Vaira D, Spigelman M, Thomas MG (2000) An assessment of the long-term preservation of the DNA of a bacterial pathogen in ethanol-preserved archival material. The Journal of pathology, 192 (4): 554 - 559. doi: 10.1002/1096-9896(2000)9999:9999<::AID-PATH768>3.0.CO;2-C

Barnes I, Young JPW, Dobney KM (2000) DNA-based identification of goose species from two archaeological sites in Lincolnshire. Journal of Archaeological Science, 27 : 91 - 100.

Barnes I, Dobney KM, Young JPW (1998) The molecular palaeoecology of geese: identification of archaeological goose remains using ancient DNA analysis. International Journal of Osteoarchaeology, 8 : 280 - 287.

Tuross N, Barnes I, Potts R (1996) Protein identification of blood residues on experimental stone tools. Journal of Archaeological Science, 23 : 289 - 296.

Highlighted publications

Meiri M, Lister AM, Collins MJ, Tuross N, Goebel T, et al (2014) Faunal record identifies Bering isthmus conditions as constraint to end-Pleistocene migration to the New World. Proceedings of the Royal Society B: Biological Sciences, 281 (1776): 20132167 - 20132167. doi: 10.1098/rspb.2013.2167

Brace S, Palkopoulou E, Dalén L, Lister AM, Miller R, et al (2012) Serial population extinctions in a small mammal indicate Late Pleistocene ecosystem instability. Proceedings of the National Academy of Sciences, 109 (50): 20532 - 20536. doi: 10.1073/pnas.1213322109

Barnes I, Duda A, Pybus OG, Thomas MG (2011) Ancient urbanization predicts genetic resistance to tuberculosis. Evolution, 65 (3): 842 - 848. doi: 10.1111/j.1558-5646.2010.01132.x

Stewart JR, Lister AM, Barnes I, Dalén L (2010) Refugia revisited: individualistic responses of species in space and time. Proceedings of the Royal Society B: Biological Sciences, 277 (1682): 661 - 671. doi: 10.1098/rspb.2009.1272