Evolution
The genus Nectophrynoides originally included species now placed in separate genera - Altiphrynoides, Nimbaphrynoides and Spinophrynoides.
The relationships of species within Nectophrynoides in its present restricted sense need to be re-appraised. At present the species relationships (closest relative) of N. asperginis are not known.
Genetics
Karyotype not known.
Since the global population of this species is a now the subject of two captive breeding programmes a high level of homozygosity would be expected. However, this may not be too much of a problem given their past history of rapid, apparently natural, population expansions and declines (“formerly abundant with a population of around 17,000 animals…high in May 1999…low in 2001 and 2002…population estimated at 1,000 animals…at a high again in 2003…as many as 20,000 individuals”).